bmr [2017-8-11 16:0:3]

general stress protein, multidrug-efflux transporter

Locus: BSU24010

Isoelectric point: 9.70

Molecular weight: 42.10 kDa

Protein length: 389 aa

Gene length: 1167 bp

Function: multidrug resistance

Product: multidrug-efflux transporter

Essential: no

Synonyms: bmr1

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → Transporters/ other → Other exporters
• Lifestyles → Coping with stress → General stress proteins (controlled by SigB)
• Lifestyles → Coping with stress → Resistance against toxins/ antibiotics
• Groups of genes → Membrane proteins

Gene

Coordinates: 2,494,656 → 2,495,825

The protein

Protein family

• TCR/tet family (according to Swiss-Prot)

Paralogous protein(s)

• Blt

Expression and Regulation

Operons

• Genes: bmr-bmrR
  Description: PubMed

  Sigma factors

  • SigB: sigma factor, PubMed, in SigB regulon
  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • BmrR: activation, PubMed, in BmrR regulon
  • Mta: activation, PubMed, in Mta regulon

  Regulation

  • bmrU: induced by stress (SigB) PubMed

• Genes: bmrU-bmr-bmrR
  Description: PubMed

  Sigma factors

  • SigB: sigma factor, PubMed, in SigB regulon

  Regulation

  • bmrU: induced by stress (SigB) PubMed

References

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